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    中國農大揭示植物通過自噬抗旱新機理

    發布時間:2019-08-05 作者:董魯皖龍 來源:中國教育新聞網

    中國教育新聞網訊(記者 董魯皖龍)植物不能移動,無法躲避嚴酷的自然環境。在進化過程中,聰慧的植物形成了防御干旱脅迫的復雜調控機制。受干旱脅迫影響,植物會產生錯誤折疊的垃圾蛋白,植物會通過自我清除垃圾的“自噬”方式將這些蛋白降解來維持細胞活力。植物如何通過自噬方式提高抗旱能力一直是研究熱點。

    2019年7月31日,細胞生物學領域權威期刊Autophagy(影響因子11.059)在線發表中國農業大學生物學院農業生物技術國家重點實驗室王濤教授研究團隊題為“Dehydrin MtCAS31 promotes autophagic degradation under drought stress”的研究論文。

    該團隊發現,在干旱脅迫條件下,苜蓿中脫水素蛋白大量表達,并與水通道蛋結合,進而與自噬調控蛋白形成三個蛋白質的復合體,然后蛋白復合體通過自噬途徑將水通道蛋白降解,從而降低細胞水通道蛋白的數量,減少水分蒸騰,提高細胞保水能力,抵御干旱危害。此前,脫水素一直被認為是細胞分子伴侶,主要功能是對蛋白起保護作用,本文首次揭示脫水素參與自噬并調控植物抗旱的新機制,為植物抗旱育種提供了新的理論支持。

    該研究論文李昕和劉倩雯為共同第一作者,王濤和董江麗為共同通訊作者。該課題得到國家自然科學基金的支持。

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